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The PINK1/Parkin pathway regulates mitochondrial morphology
Loss-of-function mutations in the PTEN-induced kinase 1 (PINK1) or parkin genes, which encode a mitochondrially localized serine/threonine kinase and a ubiquitin-protein ligase, respectively, result in recessive familial forms of Parkinsonism. Genetic studies in Drosophila indicate that PINK1 acts u...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234197/ https://ncbi.nlm.nih.gov/pubmed/18230723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709336105 |
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