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Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by loss of dopaminergic neurons in the substantia nigra. Several lines of evidence strongly implicate mitochondrial dysfunction as a major causative factor in PD, although the molecular mechanisms responsible for mito...

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Detalhes bibliográficos
Main Authors: Greene, Jessica C., Whitworth, Alexander J., Kuo, Isabella, Andrews, Laurie A., Feany, Mel B., Pallanck, Leo J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153051/
https://ncbi.nlm.nih.gov/pubmed/12642658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0737556100
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