Germline BRCA1 mutations increase prostate cancer risk

BACKGROUND: Prostate cancer (PrCa) is one of the most common cancers affecting men but its aetiology is poorly understood. Family history of PrCa, particularly at a young age, is a strong risk factor. There have been previous reports of increased PrCa risk in male BRCA1 mutation carriers in female b...

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Détails bibliographiques
Auteurs principaux: Leongamornlert, D, Mahmud, N, Tymrakiewicz, M, Saunders, E, Dadaev, T, Castro, E, Goh, C, Govindasami, K, Guy, M, O'Brien, L, Sawyer, E, Hall, A, Wilkinson, R, Easton, D, Goldgar, D, Eeles, R, Kote-Jarai, Z
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Genetics and Genomics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349179/
https://ncbi.nlm.nih.gov/pubmed/22516946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.146
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