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A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer

Although prostate cancer (PrCa) is one of the most common cancers in men in Western countries, little is known about the inherited factors that influence PrCa risk. On the basis of the fact that BRIP1/FANCJ interacts with BRCA1 and functions as a regulator of DNA double-strand break repair pathways,...

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Detalhes bibliográficos
Main Authors: Kote-Jarai, Z, Jugurnauth, S, Mulholland, S, Leongamornlert, D A, Guy, M, Edwards, S, Tymrakiewitcz, M, O'Brien, L, Hall, A, Wilkinson, R, Al Olama, A A, Morrison, J, Muir, K, Neal, D, Donovan, J, Hamdy, F, Easton, D F, Eeles, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634720/
https://ncbi.nlm.nih.gov/pubmed/19127258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604847
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