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A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer

Although prostate cancer (PrCa) is one of the most common cancers in men in Western countries, little is known about the inherited factors that influence PrCa risk. On the basis of the fact that BRIP1/FANCJ interacts with BRCA1 and functions as a regulator of DNA double-strand break repair pathways,...

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Bibliografiske detaljer
Main Authors: Kote-Jarai, Z, Jugurnauth, S, Mulholland, S, Leongamornlert, D A, Guy, M, Edwards, S, Tymrakiewitcz, M, O'Brien, L, Hall, A, Wilkinson, R, Al Olama, A A, Morrison, J, Muir, K, Neal, D, Donovan, J, Hamdy, F, Easton, D F, Eeles, R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634720/
https://ncbi.nlm.nih.gov/pubmed/19127258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604847
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