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Prostate Cancer Germline Variations and Implications for Screening and Treatment

Prostate cancer (PCa) is a highly heritable disease, and rapid evolution of sequencing technologies has enabled marked progression of our understanding of its genetic inheritance. A complex polygenic model that involves common low-penetrance susceptibility alleles causing individually small but cumu...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Dias, Alexander, Kote-Jarai, Zsofia, Mikropoulos, Christos, Eeles, Ros
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120689/
https://ncbi.nlm.nih.gov/pubmed/29101112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a030379
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