Germline BRCA Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer

PURPOSE: To analyze the baseline clinicopathologic characteristics of prostate tumors with germline BRCA1 and BRCA2 (BRCA1/2) mutations and the prognostic value of those mutations on prostate cancer (PCa) outcomes. PATIENTS AND METHODS: This study analyzed the tumor features and outcomes of 2,019 pa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Castro, Elena, Goh, Chee, Olmos, David, Saunders, Ed, Leongamornlert, Daniel, Tymrakiewicz, Malgorzata, Mahmud, Nadiya, Dadaev, Tokhir, Govindasami, Koveela, Guy, Michelle, Sawyer, Emma, Wilkinson, Rosemary, Ardern-Jones, Audrey, Ellis, Steve, Frost, Debra, Peock, Susan, Evans, D. Gareth, Tischkowitz, Marc, Cole, Trevor, Davidson, Rosemarie, Eccles, Diana, Brewer, Carole, Douglas, Fiona, Porteous, Mary E., Donaldson, Alan, Dorkins, Huw, Izatt, Louise, Cook, Jackie, Hodgson, Shirley, Kennedy, M. John, Side, Lucy E., Eason, Jacqueline, Murray, Alex, Antoniou, Antonis C., Easton, Douglas F., Kote-Jarai, Zsofia, Eeles, Rosalind
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2013
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641696/
https://ncbi.nlm.nih.gov/pubmed/23569316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.43.1882
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados