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The PSA(−/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration

Prostate cancer (PCa) is heterogeneous and contains both differentiated and undifferentiated tumor cells, but the relative functional contribution of these two cell populations remains unclear. Here we report distinct molecular, cellular, and tumor-propagating properties of PCa cells that express hi...

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Hlavní autoři: Qin, Jichao, Liu, Xin, Laffin, Brian, Chen, Xin, Choy, Grace, Jeter, Collene, Calhoun-Davis, Tammy, Li, Hangwen, Palapattu, Ganesh S., Pang, Shen, Lin, Kevin, Huang, Jiaoti, Ivanov, Ivan, Li, Wei, Suraneni, Mahipal V., Tang, Dean G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348510/
https://ncbi.nlm.nih.gov/pubmed/22560078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.03.009
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