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The dimanganese(II) site of Bacillus subtilis class Ib ribonucleotide reductase(,)

Class Ib ribonucleotide reductases (RNRs) use a dimanganese-tyrosyl radical cofactor, Mn(III)(2)-Y•, in their homodimeric NrdF (β2) subunit to initiate reduction of ribonucleotides to deoxyribonucleotides. The structure of the Mn(II)(2) form of NrdF is an important component in understanding O(2)-me...

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Bibliographic Details
Main Authors: Boal, Amie K., Cotruvo, Joseph A., Stubbe, JoAnne, Rosenzweig, Amy C.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348363/
https://ncbi.nlm.nih.gov/pubmed/22443445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201925t
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