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An active dimanganese(III)-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase()

Escherichia coli class Ib ribonucleotide reductase (RNR) converts nucleoside 5′-diphosphates to deoxynucleoside 5′-diphosphates and is expressed in iron-limited and oxidative stress conditions. This RNR is composed of two homodimeric subunits: α2 (NrdE), where nucleotide reduction occurs, and β2 (Nr...

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Detalhes bibliográficos
Main Authors: Cotruvo, Joseph A., Stubbe, JoAnne
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190568/
https://ncbi.nlm.nih.gov/pubmed/20070127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902106n
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