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An active dimanganese(III)-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase()

Escherichia coli class Ib ribonucleotide reductase (RNR) converts nucleoside 5′-diphosphates to deoxynucleoside 5′-diphosphates and is expressed in iron-limited and oxidative stress conditions. This RNR is composed of two homodimeric subunits: α2 (NrdE), where nucleotide reduction occurs, and β2 (Nr...

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Hlavní autoři: Cotruvo, Joseph A., Stubbe, JoAnne
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190568/
https://ncbi.nlm.nih.gov/pubmed/20070127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902106n
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