U1-snRNP activates the NLRP3 inflammasome in human monocytes

The NLRP3 (NOD-like receptor family, pyrin domain containing 3) inflammasome is a caspase-1-containing cytosolic protein complex that is essential for processing and secretion of IL-1β. The U1-small nuclear ribonucleoprotein (U1-snRNP) which includes U1-small nuclear RNA (U1-snRNA) is a highly conse...

Full description

Saved in:
Bibliographic Details
Main Authors: Shin, Min Sun, Kang, Youna, Lee, Naeun, Kim, Sang Hyun, Kang, Ki Soo, Lazova, Rossitza, Kang, Insoo
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347773/
https://ncbi.nlm.nih.gov/pubmed/22490866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103355
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items