Macrophage migration inhibitory factor regulates U1-snRNP immune complex mediated activation of the NLRP3 inflammasome

OBJECTIVE: High expression alleles of macrophage migration inhibitory factor (MIF) are linked genetically to SLE disease severity. The U1-snRNP (snRNP) immune complex containing U1-snRNP and anti-U1-snRNP antibodies, which are found in SLE, activates the NLRP3 inflammasome comprised of NLRP3, ASC, a...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Arthritis Rheumatol
Hlavní autoři: Shin, Min Sun, Kang, Youna, Wahl, Elizabeth R., Park, Hong-Jai, Lazova, Rossitza, Leng, Lin, Mamula, Mark, Krishnaswamy, Smita, Bucala, Richard, Kang, Insoo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310104/
https://ncbi.nlm.nih.gov/pubmed/30009530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40672
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky