Mouse Prion Protein (PrP) Segment 100 to 104 Regulates Conversion of PrP(C) to PrP(Sc) in Prion-Infected Neuroblastoma Cells

Prion diseases are characterized by the replicative propagation of disease-associated forms of prion protein (PrP(Sc); PrP refers to prion protein). The propagation is believed to proceed via two steps; the initial binding of the normal form of PrP (PrP(C)) to PrP(Sc) and the subsequent conversion o...

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Bibliografiske detaljer
Main Authors: Hara, Hideyuki, Okemoto-Nakamura, Yuko, Shinkai-Ouchi, Fumiko, Hanada, Kentaro, Yamakawa, Yoshio, Hagiwara, Ken'ichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Prions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347255/
https://ncbi.nlm.nih.gov/pubmed/22398286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06606-11
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