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A Camelid Anti-PrP Antibody Abrogates PrP(Sc) Replication in Prion-Permissive Neuroblastoma Cell Lines

The development of antibodies effective in crossing the blood brain barrier (BBB), capable of accessing the cytosol of affected cells and with higher affinity for PrP(Sc) would be of paramount importance in arresting disease progression in its late stage and treating individuals with prion diseases....

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Detalhes bibliográficos
Main Authors: Jones, Daryl Rhys, Taylor, William Alexander, Bate, Clive, David, Monique, Tayebi, Mourad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842437/
https://ncbi.nlm.nih.gov/pubmed/20339552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009804
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