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A Camelid Anti-PrP Antibody Abrogates PrP(Sc) Replication in Prion-Permissive Neuroblastoma Cell Lines

The development of antibodies effective in crossing the blood brain barrier (BBB), capable of accessing the cytosol of affected cells and with higher affinity for PrP(Sc) would be of paramount importance in arresting disease progression in its late stage and treating individuals with prion diseases....

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Détails bibliographiques
Auteurs principaux: Jones, Daryl Rhys, Taylor, William Alexander, Bate, Clive, David, Monique, Tayebi, Mourad
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842437/
https://ncbi.nlm.nih.gov/pubmed/20339552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009804
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