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A Camelid Anti-PrP Antibody Abrogates PrP(Sc) Replication in Prion-Permissive Neuroblastoma Cell Lines

The development of antibodies effective in crossing the blood brain barrier (BBB), capable of accessing the cytosol of affected cells and with higher affinity for PrP(Sc) would be of paramount importance in arresting disease progression in its late stage and treating individuals with prion diseases....

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Autors principals: Jones, Daryl Rhys, Taylor, William Alexander, Bate, Clive, David, Monique, Tayebi, Mourad
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842437/
https://ncbi.nlm.nih.gov/pubmed/20339552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009804
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