EGFR-Mediated Carcinoma Cell Metastasis Mediated by Integrin αvβ5 Depends on Activation of c-Src and Cleavage of MUC1

Receptor tyrosine kinases and integrins play an essential role in tumor cell invasion and metastasis. We previously showed that EGF and other growth factors induce human carcinoma cell invasion and metastasis mediated by integrin αvβ5 that is prevented by Src blockade [1]. MUC1, a transmembrane glyc...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lau, Steven K. M., Shields, David J., Murphy, Eric A., Desgrosellier, Jay S., Anand, Sudarshan, Huang, Miller, Kato, Shumei, Lim, Ssang-Taek, Weis, Sara M., Stupack, Dwayne G., Schlaepfer, David D., Cheresh, David A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2012
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346745/
https://ncbi.nlm.nih.gov/pubmed/22586492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036753
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια