Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques

Antiretroviral entry inhibitors are now being considered as vaginally administered microbicide candidates for the prevention of the sexual transmission of human immunodeficiency virus. Previous studies testing the entry inhibitors maraviroc and CMPD167 in aqueous gel formulations showed efficacy in...

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Bibliografiske detaljer
Main Authors: Malcolm, R. Karl, Veazey, Ronald S., Geer, Leslie, Lowry, Deborah, Fetherston, Susan M., Murphy, Diarmaid J., Boyd, Peter, Major, Ian, Shattock, Robin J., Klasse, Per Johan, Doyle, Lara A., Rasmussen, Kelsi K., Goldman, Laurie, Ketas, Thomas J., Moore, John P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346641/
https://ncbi.nlm.nih.gov/pubmed/22330914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05810-11
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