Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques

Antiretroviral entry inhibitors are now being considered as vaginally administered microbicide candidates for the prevention of the sexual transmission of human immunodeficiency virus. Previous studies testing the entry inhibitors maraviroc and CMPD167 in aqueous gel formulations showed efficacy in...

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Bibliografische gegevens
Hoofdauteurs: Malcolm, R. Karl, Veazey, Ronald S., Geer, Leslie, Lowry, Deborah, Fetherston, Susan M., Murphy, Diarmaid J., Boyd, Peter, Major, Ian, Shattock, Robin J., Klasse, Per Johan, Doyle, Lara A., Rasmussen, Kelsi K., Goldman, Laurie, Ketas, Thomas J., Moore, John P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346641/
https://ncbi.nlm.nih.gov/pubmed/22330914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05810-11
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