First Pharmacokinetic and Safety Study in Humans of the Novel Lipid Antiviral Conjugate CMX001, a Broad-Spectrum Oral Drug Active against Double-Stranded DNA Viruses

CMX001 is a novel, broad-spectrum lipid antiviral conjugate (LAC) that produces high intracellular levels of the active antiviral agent cidofovir diphosphate (CDV-PP). Study CMX001-102 was a randomized, double-blind, placebo-controlled, parallel group, dose-escalating study in healthy volunteers. Th...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Painter, Wendy, Robertson, Alice, Trost, Lawrence C., Godkin, Susan, Lampert, Bernhard, Painter, George
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346600/
https://ncbi.nlm.nih.gov/pubmed/22391537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05983-11
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares