Development of CMX001 for the Treatment of Poxvirus Infections

CMX001 (phosphonic acid, [[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]mono[3-(hexadecyloxy)propyl] ester) is a lipid conjugate of the acyclic nucleotide phosphonate, cidofovir (CDV). CMX001 is currently in Phase II clinical trials for the prophylaxis of human cytomegalovi...

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Detalhes bibliográficos
Main Authors: Lanier, Randall, Trost, Lawrence, Tippin, Tim, Lampert, Bernhard, Robertson, Alice, Foster, Scott, Rose, Michelle, Painter, Wendy, O’Mahony, Rose, Almond, Merrick, Painter, George
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2010
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077800/
https://ncbi.nlm.nih.gov/pubmed/21499452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2122740
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