Efficacy of CMX001 as a Post Exposure Antiviral in New Zealand White Rabbits Infected with Rabbitpox Virus, a Model for Orthopoxvirus Infections of Humans

CMX001, a lipophilic nucleotide analog formed by covalently linking 3-(hexdecyloxy)propan-1-ol to cidofovir (CDV), is being developed as a treatment for smallpox. In the absence of human cases of smallpox, new treatments must be tested for efficacy in animal models. Previously, we demonstrated the e...

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Detalhes bibliográficos
Main Authors: Rice, Amanda D., Adams, Mathew M., Wallace, Greg, Burrage, Andrew M., Lindsey, Scott F., Smith, Andrew J., Swetnam, Daniele, Manning, Brandi R., Gray, Stacey A., Lampert, Bernhard, Foster, Scott, Lanier, Randall, Robertson, Alice, Painter, George, Moyer, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046869/
https://ncbi.nlm.nih.gov/pubmed/21373379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v3010047
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