Modulation of Anti-Tumor Necrosis Factor Alpha (TNF-α) Antibody Secretion in Mice Immunized with TNF-α Kinoid

Tumor necrosis factor alpha (TNF-α) blockade is an effective treatment for patients with TNF-α-dependent chronic inflammatory diseases, such as rheumatoid arthritis, Crohn's disease, and psoriasis. TNF-α kinoid, a heterocomplex of human TNF-α and keyhole limpet hemocyanin (KLH) (TNF-K), is an a...

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Bibliographic Details
Main Authors: Assier, Eric, Semerano, Luca, Duvallet, Emilie, Delavallée, Laure, Bernier, Emilie, Laborie, Marion, Grouard-Vogel, Géraldine, Larcier, Patrick, Bessis, Natacha, Boissier, Marie-Christophe
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346328/
https://ncbi.nlm.nih.gov/pubmed/22441388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05649-11
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