Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia

During pathological pain, the actions of the endocannabinoid system, including the cannabinoid 2 receptor (CB(2)R), leads to effective anti-allodynia and modifies a variety of spinal microglial and astrocyte responses. Here, following spinal administration of the CB(2)R compound, AM1241, we examined...

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Detalhes bibliográficos
Main Authors: Wilkerson, Jenny L, Gentry, Katherine R, Dengler, Ellen C, Wallace, James A, Kerwin, Audra A, Kuhn, Megan N, Zvonok, Alexander M, Thakur, Ganesh A, Makriyannis, Alexandros, Milligan, Erin D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345359/
https://ncbi.nlm.nih.gov/pubmed/22574283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.44
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