Peripheral versus central mechanisms of the cannabinoid type 2 receptor agonist AM1710 in a mouse model of neuropathic pain

The CB(2)R agonist AM1710, examined in animal models of peripheral neuropathy, is effective in controlling aberrant light touch sensitivity, referred to as mechanical allodynia. However, nonspecific binding of AM1710 to CB(1)R, either peripherally or centrally, could be partially responsible for the...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Brain Behav
Auteurs principaux: Wilkerson, Jenny L., Alberti, Lauren B., Kerwin, Audra A., Ledent, Catherine A., Thakur, Ganesh A., Makriyannis, Alexandros, Milligan, Erin D.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749576/
https://ncbi.nlm.nih.gov/pubmed/32977358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1850
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires