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Single-molecule assays reveal that RNA localization signals regulate dynein-dynactin copy number on individual transcript cargoes
Subcellular localization of mRNAs by cytoskeletal motors plays critical roles in the spatial control of protein function(1). However, optical limitations of studying mRNA transport in vivo mean that there is little mechanistic insight into how transcripts are packaged and linked to motors, and how t...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343632/ https://ncbi.nlm.nih.gov/pubmed/22366687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2446 |
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