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The absence of a mitochondrial genome in rho(0) yeast cells extends lifespan independently of retrograde regulation

The absence of mtDNA in rho(0) yeast cells affects both respiration and mitochondrial-nuclear communication (e.g., retrograde regulation, intergenomic signaling, or pleiotropic drug resistance). Previously, it has been reported that some rho(0) strains have increased replicative lifespans, attributa...

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Autors principals: Woo, Dong Kyun, Poyton, Robert O.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341797/
https://ncbi.nlm.nih.gov/pubmed/19285548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2009.03.001
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