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Overexpression of a single ORF can extend chronological lifespan in yeast if retrograde signaling and stress response are stimulated
Systematic collections of single-gene deletions have been invaluable in uncovering determinants of lifespan in yeast. Overexpression of a single gene does not have such a clear outcome as cancellation of its function but it can lead to a variety of imbalances, deregulations and compensations, and so...
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| Udgivet i: | Biogerontology |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Netherlands
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8266792/ https://ncbi.nlm.nih.gov/pubmed/34052951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-021-09924-z |
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