Loss of Mitochondrial Membrane Potential Triggers the Retrograde Response Extending Yeast Replicative Lifespan

In the budding yeast Saccharomyces cerevisiae, loss of mitochondrial DNA (rho(0)) can induce the retrograde response under appropriate conditions, resulting in increased replicative lifespan (RLS). Although the retrograde pathway has been extensively elaborated, the nature of the mitochondrial signa...

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Bibliografiska uppgifter
Huvudupphovsmän: Miceli, Michael V., Jiang, James C., Tiwari, Anurag, Rodriguez-Quiñones, Jose F., Jazwinski, S. Michal
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Research Foundation 2012
Ämnen:
Genetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266616/
https://ncbi.nlm.nih.gov/pubmed/22303396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00102
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