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Loss of Mitochondrial Membrane Potential Triggers the Retrograde Response Extending Yeast Replicative Lifespan

In the budding yeast Saccharomyces cerevisiae, loss of mitochondrial DNA (rho(0)) can induce the retrograde response under appropriate conditions, resulting in increased replicative lifespan (RLS). Although the retrograde pathway has been extensively elaborated, the nature of the mitochondrial signa...

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Main Authors: Miceli, Michael V., Jiang, James C., Tiwari, Anurag, Rodriguez-Quiñones, Jose F., Jazwinski, S. Michal
格式: Artigo
語言:Inglês
出版: Frontiers Research Foundation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266616/
https://ncbi.nlm.nih.gov/pubmed/22303396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00102
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