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Loss of Mitochondrial Membrane Potential Triggers the Retrograde Response Extending Yeast Replicative Lifespan

In the budding yeast Saccharomyces cerevisiae, loss of mitochondrial DNA (rho(0)) can induce the retrograde response under appropriate conditions, resulting in increased replicative lifespan (RLS). Although the retrograde pathway has been extensively elaborated, the nature of the mitochondrial signa...

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Detalhes bibliográficos
Main Authors: Miceli, Michael V., Jiang, James C., Tiwari, Anurag, Rodriguez-Quiñones, Jose F., Jazwinski, S. Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266616/
https://ncbi.nlm.nih.gov/pubmed/22303396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00102
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