Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors

Polycystic kidney disease (PKD) is a ciliopathy characterized by renal cysts and hypertension. These changes are presumably due to altered fluid and electrolyte transport in the collecting duct (CD). This is the site where vasopressin (AVP) stimulates vasopressin-2 receptor (V2R)-mediated aquaporin-...

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Detalhes bibliográficos
Main Authors: Saigusa, Takamitsu, Reichert, Ryan, Guare, Jennifer, Siroky, Brian J., Gooz, Monika, Steele, Stacy, Fenton, Robert A., Bell, P. Darwin, Kolb, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340932/
https://ncbi.nlm.nih.gov/pubmed/22205228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00253.2011
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