Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors

Polycystic kidney disease (PKD) is a ciliopathy characterized by renal cysts and hypertension. These changes are presumably due to altered fluid and electrolyte transport in the collecting duct (CD). This is the site where vasopressin (AVP) stimulates vasopressin-2 receptor (V2R)-mediated aquaporin-...

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Main Authors: Saigusa, Takamitsu, Reichert, Ryan, Guare, Jennifer, Siroky, Brian J., Gooz, Monika, Steele, Stacy, Fenton, Robert A., Bell, P. Darwin, Kolb, Robert J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2012
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340932/
https://ncbi.nlm.nih.gov/pubmed/22205228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00253.2011
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