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Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors
Polycystic kidney disease (PKD) is a ciliopathy characterized by renal cysts and hypertension. These changes are presumably due to altered fluid and electrolyte transport in the collecting duct (CD). This is the site where vasopressin (AVP) stimulates vasopressin-2 receptor (V2R)-mediated aquaporin-...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340932/ https://ncbi.nlm.nih.gov/pubmed/22205228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00253.2011 |
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