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Aberrant Macrophages Mediate Defective Kidney Repair that Triggers Nephritis in Lupus-Susceptible Mice
Colony stimulating factor 1 (CSF-1), required for macrophage (Mø) survival, proliferation and activation, is upregulated in the tubular epithelial cells (TEC) during kidney inflammation. CSF-1 mediates Mø-dependent destruction in lupus-susceptible mice with nephritis and paradoxically, Mø-dependent...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340928/ https://ncbi.nlm.nih.gov/pubmed/22467656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102154 |
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