Aberrant Macrophages Mediate Defective Kidney Repair that Triggers Nephritis in Lupus-Susceptible Mice

Colony stimulating factor 1 (CSF-1), required for macrophage (Mø) survival, proliferation and activation, is upregulated in the tubular epithelial cells (TEC) during kidney inflammation. CSF-1 mediates Mø-dependent destruction in lupus-susceptible mice with nephritis and paradoxically, Mø-dependent...

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Bibliografiske detaljer
Main Authors: Iwata, Yasunori, Boström, Elisabeth A., Menke, Julia, Rabacal, Whitney A., Morel, Laurence, Wada, Takashi, Kelley, Vicki R.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340928/
https://ncbi.nlm.nih.gov/pubmed/22467656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102154
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