Distinct Roles of CSF-1 Isoforms in Lupus Nephritis

Colony-stimulating factor-1 (CSF-1), the principal growth factor for macrophages, is increased in the kidney, serum, and urine of patients with lupus nephritis, and eliminating CSF-1 suppresses lupus in MRL-Fas(lpr) mice. CSF-1 has three biologically active isoforms: a membrane-spanning cell surface...

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Autors principals: Menke, Julia, Iwata, Yasunori, Rabacal, Whitney A., Basu, Ranu, Stanley, E. Richard, Kelley, Vicki R.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2011
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187183/
https://ncbi.nlm.nih.gov/pubmed/21885670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011010038
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