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Distinct Roles of CSF-1 Isoforms in Lupus Nephritis
Colony-stimulating factor-1 (CSF-1), the principal growth factor for macrophages, is increased in the kidney, serum, and urine of patients with lupus nephritis, and eliminating CSF-1 suppresses lupus in MRL-Fas(lpr) mice. CSF-1 has three biologically active isoforms: a membrane-spanning cell surface...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187183/ https://ncbi.nlm.nih.gov/pubmed/21885670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011010038 |
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