טוען...
A cardiac microRNA governs systemic energy homeostasis by regulation of MED13
Obesity, type 2 diabetes and heart failure are associated with aberrant cardiac metabolism. We show that the heart regulates systemic energy homeostasis via MED13, a subunit of the Mediator complex, which controls transcription by thyroid hormone and other nuclear hormone receptors. MED13, in turn,...
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| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340581/ https://ncbi.nlm.nih.gov/pubmed/22541436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.029 |
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