An Endothelial-specific microRNA Governs Vascular Integrity and Angiogenesis

Endothelial cells play essential roles in maintenance of vascular integrity, angiogenesis and wound repair. We show that an endothelial cell-restricted microRNA (miR-126) mediates developmental angiogenesis in vivo. Targeted deletion of miR-126 in mice causes leaky vessels, hemorrhaging, and partial...

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Bibliografiske detaljer
Main Authors: Wang, Shusheng, Aurora, Arin B., Johnson, Brett A., Qi, Xiaoxia, McAnally, John, Hill, Joseph A., Richardson, James A., Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685763/
https://ncbi.nlm.nih.gov/pubmed/18694565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.07.002
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