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An Endothelial-specific microRNA Governs Vascular Integrity and Angiogenesis
Endothelial cells play essential roles in maintenance of vascular integrity, angiogenesis and wound repair. We show that an endothelial cell-restricted microRNA (miR-126) mediates developmental angiogenesis in vivo. Targeted deletion of miR-126 in mice causes leaky vessels, hemorrhaging, and partial...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685763/ https://ncbi.nlm.nih.gov/pubmed/18694565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.07.002 |
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