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An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133
The muscle-specific microRNAs, miR-1 and miR-133, play important roles in muscle growth and differentiation. Here, we show that the MEF2 transcription factor, an essential regulator of muscle development, directly activates transcription of a bicistronic primary transcript encoding miR-1-2 and 133a-...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409229/ https://ncbi.nlm.nih.gov/pubmed/18093911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710558105 |
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