A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism

The Mediator complex governs gene expression by linking upstream signaling pathways with the basal transcriptional machinery. However, how individual Mediator subunits may function in different tissues remains to be investigated. Through skeletal muscle-specific deletion of the Mediator subunit MED1...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Amoasii, Leonela, Holland, William, Sanchez-Ortiz, Efrain, Baskin, Kedryn K., Pearson, Mackenzie, Burgess, Shawn C., Nelson, Benjamin R., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762428/
https://ncbi.nlm.nih.gov/pubmed/26883362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.273128.115
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