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MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver

The heart requires a continuous supply of energy but has little capacity for energy storage and thus relies on exogenous metabolic sources. We previously showed that cardiac MED13 modulates systemic energy homeostasis in mice. Here, we sought to define the extra-cardiac tissue(s) that respond to car...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Baskin, Kedryn K, Grueter, Chad E, Kusminski, Christine M, Holland, William L, Bookout, Angie L, Satapati, Santosh, Kong, Y Megan, Burgess, Shawn C, Malloy, Craig R, Scherer, Philipp E, Newgard, Christopher B, Bassel-Duby, Rhonda, Olson, Eric N
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287978/
https://ncbi.nlm.nih.gov/pubmed/25422356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404218
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