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MED12 regulates a transcriptional network of calcium-handling genes in the heart

The Mediator complex regulates gene transcription by linking basal transcriptional machinery with DNA-bound transcription factors. The activity of the Mediator complex is mainly controlled by a kinase submodule that is composed of 4 proteins, including MED12. Although ubiquitously expressed, Mediato...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Baskin, Kedryn K., Makarewich, Catherine A., DeLeon, Susan M., Ye, Wenduo, Chen, Beibei, Beetz, Nadine, Schrewe, Heinrich, Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518564/
https://ncbi.nlm.nih.gov/pubmed/28724790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91920
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