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Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides

Micropeptides function as master regulators of calcium-dependent signaling in muscle. Sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA), the membrane pump that promotes muscle relaxation by taking up Ca(2+) into the sarcoplasmic reticulum, is directly inhibited by three muscle-specific micropeptides...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Anderson, Douglas M., Makarewich, Catherine A., Anderson, Kelly M., Shelton, John M., Bezprozvannaya, Svetlana, Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696797/
https://ncbi.nlm.nih.gov/pubmed/27923914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaj1460
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