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Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*

Obesity and metabolic syndrome are associated with mitochondrial dysfunction and deranged regulation of metabolic genes. Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β) is a transcriptional coactivator that regulates metabolism and mitochondrial biogenesis through stimulation of...

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Autori principali: Carrer, Michele, Liu, Ning, Grueter, Chad E., Williams, Andrew H., Frisard, Madlyn I., Hulver, Matthew W., Bassel-Duby, Rhonda, Olson, Eric N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458360/
https://ncbi.nlm.nih.gov/pubmed/22949648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207605109
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