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A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance

Myosin is the primary regulator of muscle strength and contractility. Here we show that three myosin genes, Myh6, Myh7, and Myh7b, encode related microRNAs (miRNAs) within their introns, which, in turn, control muscle myosin content, myofiber identity and muscle performance. Within the adult heart,...

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Detalles Bibliográficos
Main Authors: van Rooij, Eva, Quiat, Daniel, Johnson, Brett A., Sutherland, Lillian B., Qi, Xiaoxia, Richardson, James A., Kelm, Robert J., Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796371/
https://ncbi.nlm.nih.gov/pubmed/19922871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.10.013
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