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A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance

Myosin is the primary regulator of muscle strength and contractility. Here we show that three myosin genes, Myh6, Myh7, and Myh7b, encode related microRNAs (miRNAs) within their introns, which, in turn, control muscle myosin content, myofiber identity and muscle performance. Within the adult heart,...

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Detalhes bibliográficos
Main Authors: van Rooij, Eva, Quiat, Daniel, Johnson, Brett A., Sutherland, Lillian B., Qi, Xiaoxia, Richardson, James A., Kelm, Robert J., Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796371/
https://ncbi.nlm.nih.gov/pubmed/19922871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.10.013
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