Influenza and SARS-Coronavirus Activating Proteases TMPRSS2 and HAT Are Expressed at Multiple Sites in Human Respiratory and Gastrointestinal Tracts

The type II transmembrane serine proteases TMPRSS2 and HAT activate influenza viruses and the SARS-coronavirus (TMPRSS2) in cell culture and may play an important role in viral spread and pathogenesis in the infected host. However, it is at present largely unclear to what extent these proteases are...

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Detalhes bibliográficos
Main Authors: Bertram, Stephanie, Heurich, Adeline, Lavender, Hayley, Gierer, Stefanie, Danisch, Simon, Perin, Paula, Lucas, Jared M., Nelson, Peter S., Pöhlmann, Stefan, Soilleux, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340400/
https://ncbi.nlm.nih.gov/pubmed/22558251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035876
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