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Expression and Genetic Loss of Function Analysis of the HAT/DESC Cluster Proteases TMPRSS11A and HAT

Genome mining at the turn of the millennium uncovered a new family of type II transmembrane serine proteases (TTSPs) that comprises 17 members in humans and 19 in mice. TTSPs phylogenetically belong to one of four subfamilies: matriptase, hepsin/TMPRSS, corin and HAT/DESC. Whereas a wealth of inform...

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Detalhes bibliográficos
Main Authors: Sales, Katiuchia Uzzun, Hobson, John P., Wagenaar-Miller, Rebecca, Szabo, Roman, Rasmussen, Amber L., Bey, Alexandra, Shah, Maham F., Molinolo, Alfredo A., Bugge, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154331/
https://ncbi.nlm.nih.gov/pubmed/21853097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023261
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