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c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase

The progression and negative outcome of a variety of human carcinomas is intimately associated with aberrant activity of the c-Met oncogene. The underlying cause of this dysregulation, however, remains a subject of discussion, as the majority of cancer patients do not present with activating mutatio...

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Detalhes bibliográficos
Main Authors: Szabo, Roman, Rasmussen, Amber L., Moyer, Amanda B., Kosa, Peter, Schafer, Jeffrey M., Molinolo, Alfredo A., Gutkind, J. Silvio, Bugge, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084339/
https://ncbi.nlm.nih.gov/pubmed/21217780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.586
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