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Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway

A pericellular proteolytic pathway initiated by the transmembrane serine protease matriptase plays a critical role in the terminal differentiation of epidermal tissues. Matriptase is constitutively expressed in multiple other epithelia, suggesting a putative role of this membrane serine protease in...

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Detalhes bibliográficos
Main Authors: List, Karin, Kosa, Peter, Szabo, Roman, Bey, Alexandra L., Wang, Chao Becky, Molinolo, Alfredo, Bugge, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751542/
https://ncbi.nlm.nih.gov/pubmed/19717635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090240
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