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Design and Receptor Interactions of Obligate Dimeric Mutant of Chemokine Monocyte Chemoattractant Protein-1 (MCP-1)

Chemokine-receptor interactions regulate leukocyte trafficking during inflammation. CC chemokines exist in equilibrium between monomeric and dimeric forms. Although the monomers can activate chemokine receptors, dimerization is required for leukocyte recruitment in vivo, and it remains controversial...

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Bibliografski detalji
Glavni autori: Tan, Joshua H. Y., Canals, Meritxell, Ludeman, Justin P., Wedderburn, Jamie, Boston, Christopher, Butler, Stephen J., Carrick, Ann Marie, Parody, Todd R., Taleski, Deni, Christopoulos, Arthur, Payne, Richard J., Stone, Martin J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340267/
https://ncbi.nlm.nih.gov/pubmed/22396538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334201
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