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Influence of Chemokine N-Terminal Modification on Biased Agonism at the Chemokine Receptor CCR1

Leukocyte migration, a hallmark of the inflammatory response, is stimulated by the interactions between chemokines, which are expressed in injured or infected tissues, and chemokine receptors, which are G protein-coupled receptors (GPCRs) expressed in the leukocyte plasma membrane. One mechanism for...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sanchez, Julie, Lane, J. Robert, Canals, Meritxell, Stone, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566870/
https://ncbi.nlm.nih.gov/pubmed/31096719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102417
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