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Biased Agonism as a Mechanism for Differential Signaling by Chemokine Receptors
Chemokines display considerable promiscuity with multiple ligands and receptors shared in common, a phenomenon that is thought to underlie their biochemical “redundancy.” Their receptors are part of a larger seven-transmembrane receptor superfamily, commonly referred to as G protein-coupled receptor...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853256/ https://ncbi.nlm.nih.gov/pubmed/24145037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479113 |
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